Pasithea Clinics

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About Ketamine

Discover the story of Ketamine, and its new effective use in treating psychiatric and pain conditions.

What is Ketamine?

Ketamine was first discovered in the 1950s in Belgium and was latter approved by the FDA in 1970 as an anesthetic agent. Since then, it has been used in medical settings on a daily basis, and over the last 50 years has shown an impressive safety record. More recently over the past 20 years, researchers have discovered that Ketamine has strong antidepressant effects and stimulates the brain to create new neural pathways. Making it effective at treating certain types of psychiatric and pain conditions more effectively than traditional medications being used today. Pushing it to be used all over the world by many doctors as an off-label medication to help their patients.

Who is it beneficial for?

Several studies done over the course of the last 20 years have shown that Ketamine is highly effective helping patients that are not responding to other traditional medications. Pushing many doctors to use it to help patients that are considered treatment resistant, meaning that the current type of medications are not offering relief of their symptoms. Ketamine is 70% effective in helping these patients, who otherwise have little to no other alternative to get the relief they deserve.

you shouldn't try ketamine if?

you shouldn't try ketamine if?

What are the side effects?

During Treatment

During your treatment there are certain side effects that may occur, such as: 

These side effects however are transient and will resolve by the end of your treatment. These normally peak within 30min of administration and resolve within 1-2 hours 

After Treatment

Throughout the different studies made with Ketamine being used for both psychiatric conditions and pain management there has been close to no long-term side effects. However in cases where Ketamine is abused daily in non-medical setting it has been shown to cause liver damage.

IV Ketamine treatment comparisons

IV Ketamine vs Traditional Anti-Depressants (SSRIs)

IV Ketamine vs Traditional Pain Medication (Opiods)

Ketamine vs Traditional Medication (SSRIs)
Ketamine Vs Traditional Pain Medication (Opioids)

Ketamine Traditional Anti-Depressants (SSRIs)
Within Days
Within 2-4 Weeks
Side Effects
Long Term
Weight Gain, Sleep problems, Migrane, Sexual Dysfunction, Psychosis, Mania
Frequency of Treatment
Typical Initial course of treatment is 6 infusions over 2-3 weeks, then patients can have maintenance infusions if necessary, which range from monthly to quarterly
Daily Dose

Is Ketamine addictive?

Similarly to many other pharmacological agents, Ketamine has also been used recreationally. Normally, when used recreationally, Ketamine is given intranasally and typically in higher doses than when used for the treatment of mental health disorders. The long-term use of Ketamine recreationally can lead to tolerance but not to physical dependence. 

However, studies have shown that when Ketamine was administered in a clinical setting for the treatment of depression, there was no subsequent increased risk of abuse. Even higher doses of Ketamine than those used clinically are not ‘rewarding’ per se, making it unlikely that they may cause addiction. However, to minimize risk, if you have a history of addictive disorders, this will be carefully reviewed by the psychiatrist, before a Ketamine session is organized.

Can I continue taking my medication?

Ketamine can be given while taking most medications and is expected for you to continue with your ongoing treatment. Our in house psychiatrist will review any medical history, advise on changes if needed before starting Ketamine treatment & advise about reducing / stopping psychiatric mediations following sessions – this way we know what’s best suited towards your needs. 

Our Treatments

Our network of doctors at Pasithea provide the latest cutting-edge treatments that are shown to be highly effective in providing the relief our patients are looking for.